Publications


2023
Dötsch, A.; Merz, B.; Louis, S.; Krems, C.; Herrmann, M.; Dörr, C.; Watzl, B.; Bub, A.; Straßburg, A.; Engelbert, A. K. (2023). Assessment of Energy and Nutrient Intake and the Intestinal Microbiome (ErNst Study): Protocol and Methods of a Cross-sectional Human Observational Study. JMIR Research Protocols, 12, Art.-Nr.: e42529. doi:10.2196/42529Full textFull text of the publication as PDF documentShareExport/share the publication
Kistner, S.; Mack, C. I.; Rist, M. J.; Krüger, R.; Egert, B.; Biniaminov, N.; Engelbert, A. K.; Seifert, S.; Dörr, C.; Ferrario, P. G.; Neumann, R.; Altmann, S.; Bub, A. (2023). Acute effects of moderate vs. vigorous endurance exercise on urinary metabolites in healthy, young men : A multi-platform metabolomics approach. Frontiers in physiology, 14, Article no: 1028643. doi:10.3389/fphys.2023.1028643Full textFull text of the publication as PDF documentShareExport/share the publication
2021
Danesi, F.; Mengucci, C.; Vita, S.; Bub, A.; Seifert, S.; Malpuech-Brugère, C.; Richard, R.; Orfila, C.; Sutulic, S.; Ricciardiello, L.; Marcato, E.; Capozzi, F.; Bordoni, A. (2021). Unveiling the Correlation between Inadequate Energy/Macronutrient Intake and Clinical Alterations in Volunteers at Risk of Metabolic Syndrome by a Predictive Model. Nutrients, 13 (4), Article no: 1377. doi:10.3390/nu13041377Full textFull text of the publication as PDF documentShareExport/share the publication
Kistner, S.; Döring, M.; Krüger, R.; Rist, M. J.; Weinert, C. H.; Bunzel, D.; Merz, B.; Radloff, K.; Neumann, R.; Härtel, S.; Bub, A. (2021). Sex-specific Relationship between the Cardiorespiratory Fitness and Plasma Metabolite Patterns in Healthy Humans—Results of the KarMeN Study. Metabolites, 11 (7), Art. Nr.: 463. doi:10.3390/metabo11070463Full textFull text of the publication as PDF documentShareExport/share the publication
2019
Bub, A.; Malpuech-Brugère, C.; Orfila, C.; Amat, J.; Arianna, A.; Blot, A.; Di Nunzio, M.; Holmes, M.; Kertész, Z.; Marshall, L.; Nemeth, I.; Ricciardiello, L.; Seifert, S.; Sutulic, S.; Ulaszewska, M.; Bordoni, A. (2019). A Dietary Intervention of Bioactive Enriched Foods Aimed at Adults at Risk of Metabolic Syndrome: Protocol and Results from PATHWAY-27 Pilot Study. Nutrients, 11 (8), 1814. doi:10.3390/nu11081814Full textFull text of the publication as PDF documentShareExport/share the publication
Ghini, V.; Tenori, L.; Capozzi, F.; Luchinat, C.; Bub, A.; Malpuech-Brugere, C.; Orfila, C.; Ricciardiello, L.; Bordoni, A. (2019). DHA-Induced Perturbation of Human Serum Metabolome. Role of the Food Matrix and Co-Administration of Oat β-glucan and Anthocyanins. Nutrients, 12 (1), 86. doi:10.3390/nu12010086Full textFull text of the publication as PDF documentShareExport/share the publication
Mack, C. I.; Egert, B.; Liberto, E.; Weinert, C. H.; Bub, A.; Hoffmann, I.; Bicchi, C.; Kulling, S. E.; Cordero, C. (2019). Robust Markers of Coffee Consumption Identified Amongst the Volatile Organic Compounds in Human Urine. Molecular nutrition & food research, 63 (10), Article: 1801060. doi:10.1002/mnfr.201801060ShareExport/share the publication
Ulaszewska, M. M.; Weinert, C. H.; Trimigno, A.; Portmann, R.; Andres Lacueva, C.; Badertscher, R.; Brennan, L.; Brunius, C.; Bub, A.; Capozzi, F.; Cialiè Rosso, M.; Cordero, C. E.; Daniel, H.; Durand, S.; Egert, B.; Ferrario, P. G.; Feskens, E. J. M.; Franceschi, P.; Garcia-Aloy, M.; Giacomoni, F.; Giesbertz, P.; González-Domínguez, R.; Hanhineva, K.; Hemeryck, L. Y.; Kopka, J.; Kulling, S. E.; Llorach, R.; Manach, C.; Mattivi, F.; Migné, C.; Münger, L. H.; Ott, B.; Picone, G.; Pimentel, G.; Pujos-Guillot, E.; Riccadonna, S.; Rist, M. J.; Rombouts, C.; Rubert, J.; Skurk, T.; Sri Harsha, P. S. C.; Van Meulebroek, L.; Vanhaecke, L.; Vázquez-Fresno, R.; Wishart, D.; Vergères, G. (2019). Nutrimetabolomics: An Integrative Action for Metabolomic Analyses in Human Nutritional Studies. Molecular nutrition & food research, 63 (1), 1800384. doi:10.1002/mnfr.201800384ShareExport/share the publication
Vázquez-Manjarrez, N.; Weinert, C. H.; Ulaszewska, M. M.; Mack, C. I.; Micheau, P.; Pétéra, M.; Durand, S.; Pujos-Guillot, E.; Egert, B.; Mattivi, F.; Bub, A.; Dragsted, L. O.; Kulling, S. E.; Manach, C. (2019). Discovery and Validation of Banana Intake Biomarkers Using Untargeted Metabolomics in Human Intervention and Cross-sectional Studies. The journal of nutrition, 149 (10), 1701–1713. doi:10.1093/jn/nxz125ShareExport/share the publication
2018
Armbruster, M.; Rist, M. J.; Seifert, S.; Frommherz, L.; Weinert, C. H.; Mack, C.; Roth, A.; Merz, B.; Bunzel, D.; Krüger, R.; Kulling, S. E.; Watzl, B.; Bub, A. (2018). Metabolite profiles evaluated, according to sex, do not predict resting energy expenditure and lean body mass in healthy non-obese subjects. European journal of nutrition, 1–11. doi:10.1007/s00394-018-1767-1ShareExport/share the publication
Mack, C. I.; Weinert, C. H.; Egert, B.; Ferrario, P. G.; Bub, A.; Hoffmann, I.; Watzl, B.; Daniel, H.; Kulling, S. E. (2018). The complex human urinary sugar profile: determinants revealed in the cross-sectional KarMeN study. The American journal of clinical nutrition, 108 (3), 502–516. doi:10.1093/ajcn/nqy131ShareExport/share the publication
2017
Krüger, R.; Merz, B.; Rist, M. J.; Ferrario, P. G.; Bub, A.; Kulling, S. E.; Watzl, B. (2017). Associations of current diet with plasma and urine TMAO in the KarMeN study : direct and indirect contributions. Molecular nutrition & food research, 61 (11), Art.Nr. 1700363. doi:10.1002/mnfr.201700363ShareExport/share the publication
2016
Bub, A.; Kriebel, A.; Dörr, C.; Bandt, S.; Rist, M. J.; Roth, A.; Hummel, E.; Hoffmann, I.; Kulling, S. E.; Watzl, B. (2016). The Karlsruhe Metabolomics and Nutrition (KarMeN) Study: Protocol and Methods of a cross-sectional study to characterize the metabolome of healthy men and women. Journal of medical internet research / Research Protocols, 5 (3), 146 -. doi:10.2196/resprot.5792ShareExport/share the publication
Engelbert, A. K.; Soukup, S. T.; Roth, A.; Hoffmann, N.; Graf, D.; Watzl, B.; Kulling, S. E.; Bub, A. (2016). Isoflavone supplementation in postmenopausal women does not affect leukocyte LDL receptor and scavenger receptor CD36 expression: A double-blind, randomized, placebo-controlled trial. Molecular nutrition & food research, 60 (9), 2008–2019. doi:10.1002/mnfr.201600019ShareExport/share the publication
Soukup, S. T.; Helppi, J.; Müller, D. R.; Zierau, O.; Watzl, B.; Vollmer, G.; Diel, P.; Bub, A.; Kulling, S. E. (2016). Phase II metabolism of the soy isoflavones genistein and daidzein in humans, rats and mice: a sex and cross-species comparison. Archives of toxicology, 90 (6), 1335–47. doi:10.1007/s00204-016-1663-5ShareExport/share the publication
2015
Cho, G.-S.; König, A.; Seifert, S.; Hanak, A.; Roth, A.; Huch, M.; Bub, A.; Watzl, B.; Franz, C. M. A. P. (2015). Comparative study of the fecal microbiota in patients with type II diabetes after consumption of apple juice for 4 weeks. Food science and biotechnology, 24 (6), 2083–2094. doi:10.1007/s10068-015-0277-7ShareExport/share the publication
Souverein, O. W.; De Vries, J. H. M.; Freese, R.; Watzl, B.; Bub, A.; Miller, E. R., III; Castenmiller, J. J. M.; Pasman, W. J.; Van Het Hof, K.; Chopra, M.; Karlsen, A.; Dragsted, L. O.; Winkels, R.; Itsiopoulos, C.; Brazionis, L.; O’Dea, K.; Van Loo-Bouwman, C. A.; Naber, T. H. J.; Van Der Voet, H.; Boshuizen, H. C. (2015). Prediction of fruit and vegetable intake from biomarkers using individual participant data of diet-controlled intervention studies. British journal of nutrition, 113 (9), 1396–1409. doi:10.1017/S0007114515000355ShareExport/share the publication
Wiese, S.; Esatbeyoglu, T.; Winterhalter, P.; Kruse, H.-P.; Winkler, S.; Bub, A.; Kulling, S. E. (2015). Comparative biokinetics and metabolism of pure monomeric, dimeric, and polymeric flavan-3-ols: A randomized cross-over study in humans. Molecular nutrition & food research, 59 (4), 610–621. doi:10.1002/mnfr.201400422ShareExport/share the publication
2014
Fink, A.; Rüfer, C. E.; Le Grandois, J.; Roth, A.; Aoude-Werner, D.; Marchioni, E.; Bub, A.; Barth, S. W. (2014). Dietary walnut oil modulates liver steatosis in the obese Zucker rat. European journal of nutrition, 53 (2), 645–660. doi:10.1007/s00394-013-0573-zShareExport/share the publication
Graf, D.; Barth, S. W.; Bub, A.; Narr, J.; Rüfer, C. E.; Watzl, B.; Seifert, S. (2014). Dietary fat quality in regular fat diets has minor effects on biomarkers of inflammation in obese Zucker rats. European journal of nutrition, 53 (1), 211–219. doi:10.1007/s00394-013-0518-6ShareExport/share the publication
2013
Bode, L. M.; Bunzel, D.; Huch, M.; Cho, G.-S.; Ruhland, D.; Bunzel, M.; Bub, A.; Franz, C. M. A. P.; Kulling, S. E. (2013). In vivo and in vitro metabolism of trans-resveratrol by human gut microbiota. The American journal of clinical nutrition, 97 (2), 295–309. doi:10.3945/ajcn.112.049379ShareExport/share the publication
Graf, D.; Seifert, S.; Bub, A.; Fröhling, B.; Dold, S.; Unger, F.; Römpp, A.; Watzl, B. (2013). Anthocyanin-rich juice does not affect gut-associated immunity in Fischer rats. Molecular nutrition & food research, 57 (10), 1753–1761. doi:10.1002/mnfr.201300022ShareExport/share the publication
Huch, M.; De Bruyne, K.; Cleenwerck, I.; Bub, A.; Cho, G.-S.; Watzl, B.; Snauwaert, I.; Franz, C. M. A. P.; Vandamme, P. (2013). Streptococcus rubneri sp. nov., isolated from the human throat. International journal of systematic and evolutionary microbiology, 63 (PART 11), 4026–4032. doi:10.1099/ijs.0.048538-0ShareExport/share the publication
2012
Barth, S. W.; Koch, T. C. L.; Watzl, B.; Dietrich, H.; Will, F.; Bub, A. (2012). Moderate effects of apple juice consumption on obesity-related markers in obese men: Impact of diet-gene interaction on body fat content. European journal of nutrition, 51 (7), 841–850. doi:10.1007/s00394-011-0264-6ShareExport/share the publication
Boeing, H.; Bechthold, A.; Bub, A.; Ellinger, S.; Haller, D.; Kroke, A.; Leschik-Bonnet, E.; Müller, M. J.; Oberritter, H.; Schulze, M.; Stehle, P.; Watzl, B. (2012). Critical review: Vegetables and fruit in the prevention of chronic diseases. European journal of nutrition, 51 (6), 637–663. doi:10.1007/s00394-012-0380-yShareExport/share the publication
2011
Hauder, J.; Winkler, S.; Bub, A.; Rüfer, C. E.; Pignitter, M.; Somoza, V. (2011). LC-MS/MS quantification of sulforaphane and indole-3-carbinol metabolites in human plasma and urine after dietary intake of selenium-fortified broccoli. Journal of agricultural and food chemistry, 59 (15), 8047–8057. doi:10.1021/jf201501xShareExport/share the publication
Hsu, F. C.; Wirtz, M.; Heppel, S. C.; Bogs, J.; Krämer, U.; Khan, M. S.; Bub, A.; Hell, R.; Rausch, T. (2011). Generation of Se-fortified broccoli as functional food : Impact of Se-fertilization on S-metabolism. Plant, Cell & Enviroment, 34 (2), 192–207. doi:10.1111/j.1365-3040.2010.02235.xShareExport/share the publication
Pfeuffer, M.; Fielitz, K.; Laue, C.; Winkler, P.; Rubin, D.; Helwig, U.; Giller, K.; Kammann, J.; Schwedhelm, E.; Böger, R. H.; Bub, A.; Bell, D.; Schrezenmeir, J. (2011). CLA does not impair endothelial function and decreases body weight as compared to sunflower oil in overweight male subjects. Journal of the American College of Nutrition, 30 (1), 19–28. ShareExport/share the publication
Welch, R. W.; Antoine, J. M.; Berta, J. L.; Bub, A.; Vries, J. F. de; Guarner, F.; Hasselwander, O.; Hendriks, H. F. J.; Jäkel, M.; Koletzko, B. V.; Patterson, C. C.; Richelle, M. A.; Skarp, M.; Theis, S.; Vidry, S.; Woodside, J. V. (2011). Guidelines for the design, conduct and reporting of human intervention studies to evaluate the health benefits of foods. British journal of nutrition, 106 (Suppl. 2), 3–15. doi:10.1017/S0007114511003606ShareExport/share the publication
2010
Garcia, A. L.; Mohan, R.; Koebnick, C.; Bub, A.; Heuer, T.; Strassner, C.; Groeneveld, M. J.; Katz, N.; Elmadfa, I. (2010). Plasma β-carotene is not a suitable biomarker of fruit and vegetable intake in German subjects with a long-term high consumption of fruits and vegetables. Annals of nutrition & metabolism, 56 (1), 23–30. doi:10.1159/000262295ShareExport/share the publication
Stracke, B. A.; Rüfer, C. E.; Bub, A.; Barth, S. W.; Briviba, K. (2010). Epigallocatechingallat - Bioverfügbarkeit und Wirkungen auf den Glucosemetabolismus in Zucker-Ratten. Deutsche Gesellschaft für Ernährung: Abstractband zum 47. Wissenschaftlichen Kongressm, Jena, 11.-12. März 2010, 25/1–1, Deutsche Gesellschaft für Ernährung e.V. (DGE). ShareExport/share the publication
2009
Koch, T. C. L.; Briviba, K.; Watzl, B.; Fähndrich, C.; Bub, A.; Rechkemmer, G.; Barth, S. W. (2009). Prevention of colon carcinogenesis by apple juice in vivo: Impact of juice constituents and obesity. Molecular nutrition & food research, 53 (10), 1289–1302. ShareExport/share the publication
Kressel, G.; Trunz, B.; Bub, A.; Hülsmann, O.; Wolters, M.; Lichtinghagen, R.; Stichenoth, D. . O.; Hahn, A. (2009). Systemic and vascular markers of inflammation in relation to metabolic syndrome and insulin resistance in adults with elevated atherosclerosis risk. Atherosclerosis, 202 (1), 263–271. ShareExport/share the publication
Rüfer, C.; Kulling, S.; Möseneder, J.; Winterhalter, P.; Bub, A. (2009). Role of plasma lipoproteins in the transport of the soybean isoflavones daidzein and daidzein-7-O-ß-D-glucoside. British journal of nutrition, 102 (6), 793–796. ShareExport/share the publication
Stracke, B.; Ruefer, C. E.; Bub, A.; Briviba, K.; Seifert, S.; Kunz, C.; Watzl, B. (2009). Bioavailability and Nutritional Effects of Carotenoids from Organically and Conventionally Produced Carrots in Healthy Men. British journal of nutrition, 101 (11), 1664–1672. ShareExport/share the publication
Stracke, B.; Ruefer, C. E.; Weibel, F. P.; Bub, A.; Watzl, B. (2009). Three Year Comparison of the Polyphenol Content and Antioxidant Capacity in Organically and Conventionally Produced Apples (variety Golden Delicious). Journal of Agricultural and Food Chemistry, 57 (11), 4598–4605. ShareExport/share the publication
2008
Bub, A. (2008). Prävention von Herkreislauferkrankungen durch Obst und Gemüse. Journal für Ernährungsmedizin, 10 (1), 20–21. ShareExport/share the publication
Bub, A.; Möseneder, J.; Wenzel, G.; Rechkemmer, G.; Briviba, K. (2008). Zeaxanthin is bioavailable from genetically modified zeaxanthin-rich potatoes. European journal of nutrition, 47 (2), 99–103. ShareExport/share the publication
Rüfer, C.; Bub, A.; Möseneder, J.; Winterhalter, P.; Stütz, M.; Kulling, S. (2008). Pharmacokinetics of the soybean isoflavone daidzein in its aglycon and glucoside form in healthy men. American Journal of Clinical Nutrition, 87 (5), 1314–1323. ShareExport/share the publication
Rüfer, C.; Möseneder, J.; Briviba, K.; Rechkemmer, G.; Bub, A. (2008). Biovailability of Astaxanthin Stereoisomers from Wild and Aquacultured Salmon in Healthy Men: a Randomized, Double-Blind Study. British journal of nutrition, 99 (5), 1048–1054. ShareExport/share the publication
Rüfer, C. E.; Möseneder, J.; Winterhalter, P.; Kulling, S. E.; Bub, A. (2008). Rolle der Plasmalipoproteine am Transport von Isoflavonen. Abstracts zum 45. Wissenschaftlichen Kongress, Bonn, 13.-14. März 2008. Hrsg.: P. Stehle, 66/1–1, Deutsche Gesellschaft für Ernährung e.V. (DGE). ShareExport/share the publication
Schnäbele, K.; Briviba, K.; Bub, A.; Pool-Zobel, B.-L.; Rechkemmer, G. (2008). Effects of carrot and tomato juice consumption on faecal markers relevant to colon carcinogenesis in humans. British journal of nutrition, 99 (3), 606–613. ShareExport/share the publication
2005
Briviba, K.; Watzl, B.; Nickel, K.; Kulling, S.; Bös, K.; Härtel, S.; Rechkemmer, G.; Bub, A. (2005). A half-marathon and a marathon run induce oxidative DNA damage, reduce antioxidant capacity to protect DNA against damage and modify immune function in hobby runners. Redox Report, 10 (6), 325–331. ShareExport/share the publication